Cavalier King Charles Spaniel vaccination schedule
A general Cavalier King Charles Spaniel puppy vaccination schedule by age, with what each vaccine protects against. Schedules for the US, the UK and the EU. Your vet sets the actual one.
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Questions
When should my Cavalier King Charles Spaniel start vaccinations?
Most Cavalier King Charles Spaniel puppies start their first DHPP between 6 and 8 weeks in the US, or 6 to 9 weeks in the UK and EU. Use the form above with your puppy's age and country to see the next-due date.
Are Cavaliers more sensitive to vaccines?
Not specifically. Cavaliers are known for cardiac concerns, but those are unrelated to vaccines. Standard DHPP schedule applies.
Does my Cavalier need leptospirosis or Lyme?
In the US, yes: since 2024 the AAHA vaccination guidelines list leptospirosis as a core vaccine for all dogs, with two doses from 12 weeks of age and a booster every year. In the UK it is part of the usual puppy course. Elsewhere it is core where the disease is present (WSAVA), so ask your vet. Living mostly indoors does not change this: the guidelines no longer sort dogs by lifestyle for this vaccine. Lyme stays a vaccine for dogs in tick-heavy areas.
Should my Cavalier get split visits?
Usually not necessary. Cavaliers are small but not toy-sized, and most tolerate combined visits well. Ask your vet if your pup shows post-shot soreness.
Same schedule for a Cavalier King Charles Spaniel mix?
Yes. The core vaccines are the same for purebreds and mixes: DHPP, leptospirosis in the US (AAHA), and rabies where the law or travel requires it. Vaccines such as Lyme and Bordetella depend on lifestyle and region, not breed. The schedule above works for any Cavalier King Charles Spaniel mix.