Great Dane Vaccination Schedule

Personalized Great Dane puppy vaccination schedule for the US, UK, and EU. Adjust your puppy's age and country below. The schedule updates as you go.

Important: this is a reference. It is not a substitute for your vet. Always confirm the specific schedule for your puppy with the clinic that treats them.

Breed
Great Dane
Pet's age
weeks

Great Dane vaccination schedule

8 weeks (≈2 months)United States schedule

Next due: 6 to 8 weeks · DHPP #1, Bordetella #1 (if going to puppy class or daycare)

AgeStatusCoreNon-core
6 to 8 weeksDue now
  • DHPP #1
  • Bordetella #1 (if going to puppy class or daycare)
10 to 12 weeksUpcoming
  • DHPP #2
  • Leptospirosis #1 (regional)
  • Lyme #1 (regional)
14 to 16 weeksUpcoming
  • DHPP #3
  • Leptospirosis #2
  • Lyme #2
  • Bordetella
16 weeks+Required by law in most US states.Upcoming
  • Rabies #1
12 monthsUpcoming
  • DHPP booster
  • Rabies booster
  • Leptospirosis annual
  • Lyme annual
  • Bordetella annual
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Common questions about Great Dane vaccinations

When should my Great Dane start vaccinations?

Most Great Dane puppies start their first DHPP between 6 and 8 weeks in the US, or 6 to 9 weeks in the UK and EU. Use the form above with your puppy's age and country to see the next-due date.

When can my Great Dane start long walks?

After full vaccination at around 16 weeks for short walks. Long-distance walks, running, jumping, and stair work wait until growth plates close, often 18 to 24 months for giant breeds.

Should my Great Dane get titer testing later?

Many vets offer it for adult giant breeds. Discuss it after the first-year series is complete.

Are Great Danes more sensitive to vaccines?

Not specifically. Standard DHPP schedule applies. The bigger giant-breed concern is over-exercise, not vaccine reactions.

Same schedule for a Great Dane mix?

Yes for the core vaccines. DHPP and Rabies are identical for purebreds and mixes. Non-core vaccines depend on lifestyle and region, not breed. The schedule above works for any Great Dane mix.

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